F5 products LTM and GTM work just great with IPv6. But IPv6 address shortening (double-colons '::') is not permitted in the GUI or tmsh.
LTM and GTM are Linux based systems, so if you are using BASH, the standard rules apply.
But if you are using the GUI or tmsh, IPv6 addresses must be fully completed.
This: fe80:0:0:0:201:d7ff:fed4:d041 Not this: fe80::201:d7ff:fed4:d041 ^^ Cannot have a double colon.